Genetic abnormalities in mammary ductal intraepithelial neoplasia-flat type (?clinging ductal carcinoma in situ?)
نویسندگان
چکیده
منابع مشابه
Ductal Epithelial Lesions: Ductal Carcinoma In Situ vs Atypical Ductal Hyperplasia vs Flat Epithelial Atypia
Before the era of mammography, ductal carcinoma in situ (DCIS) comprised only less than 3% of newly diagnosed breast cancers, most as large palpable masses, and many with microscopic foci of invasion. With widespread use of mammography, DCIS now makes up about 25% of breast cancers diagnosed in the U.S., most as non-palpable lesions. There is also concurrent increased prevalence of atypical duc...
متن کاملDuctal carcinoma in situ.
Management of ductal carcinoma in situ (DCIS) has evolved from radical surgery to the option of a more minimally invasive approach. Data show that breast conservation surgery performed with administration of radiotherapy, like mastectomy, is feasible and safe. Because efforts to find a safe group for elimination of radiotherapy have resulted in data that conflict, radiotherapy still remains sta...
متن کاملDuctal carcinoma in situ arising in mammary hamartoma.
Hamartoma of the breast is an uncommon lesion. Although it can possess characteristic radiological features, the pathological appearance is not distinctive. Hamartoma is generally considered benign, but four cases have been reported with ductal and lobular carcinoma arising in hamartomas. This report describes further cases of hamartoma from which ductal carcinoma in situ arose, with one showin...
متن کاملBreast Ductal Carcinoma In Situ
Ductal carcinoma in situ (DCIS) of the breast is becoming one of the most important diseases diagnosed in preventive medicine screening. The current age-adjusted incidence rate of DCIS is 32.5 per 100,000 women. For women 50–64 years of age, the incidence is approximately 88 per 100,000. Currently, for every 4 diagnoses of invasive breast cancer, there is 1 diagnosis of DCIS. Risk of DCIS is ra...
متن کاملEGFR expression in pancreatic intraepithelial neoplasia and ductal adenocarcinoma.
Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignant tumor with poor prognosis. Epidermal growth factor receptor (EGFR) is an important cell adhesion and signaling pathway mediator. The aim of this study was to evaluate the expression of EGFR in both pancreatic intraepithelial neoplasia (PanIN) and PDA and their relationship to clinicopathologic characteristics. Formalin-fixed, par...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer
سال: 2000
ISSN: 0008-543X,1097-0142
DOI: 10.1002/(sici)1097-0142(20000501)88:9<2072::aid-cncr13>3.0.co;2-h